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Down-Regulation of the Interferon Signaling Pathway in T Lymphocytes from Patients with Metastatic Melanoma
BACKGROUND: Dysfunction of the immune system has been documented in many types of cancers. The precise nature and molecular basis of immune dysfunction in the cancer state are not well defined. METHODS AND FINDINGS: To gain insights into the molecular mechanisms of immune dysfunction in cancer, gene...
Autores principales: | Critchley-Thorne, Rebecca J, Yan, Ning, Nacu, Serban, Weber, Jeffrey, Holmes, Susan P, Lee, Peter P |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1865558/ https://www.ncbi.nlm.nih.gov/pubmed/17488182 http://dx.doi.org/10.1371/journal.pmed.0040176 |
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