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Hepatitis C virus epitope-specific neutralizing antibodies in Igs prepared from human plasma

Neutralizing antibodies directed against hepatitis C virus (HCV) are present in Igs made from anti-HCV-positive plasma. However, these HCV-specific Igs are largely ineffective in vivo. The mechanism for the poor effectiveness is currently unknown. We hypothesize that the presence of nonneutralizing...

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Detalles Bibliográficos
Autores principales: Zhang, Pei, Wu, Charles G., Mihalik, Kathleen, Virata, Maria Luisa, Yu, Mei-ying W., Alter, Harvey J., Feinstone, Stephen M.
Formato: Texto
Lenguaje:English
Publicado: National Academy of Sciences 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866310/
https://www.ncbi.nlm.nih.gov/pubmed/17494735
http://dx.doi.org/10.1073/pnas.0703039104