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Hepatitis C virus epitope-specific neutralizing antibodies in Igs prepared from human plasma
Neutralizing antibodies directed against hepatitis C virus (HCV) are present in Igs made from anti-HCV-positive plasma. However, these HCV-specific Igs are largely ineffective in vivo. The mechanism for the poor effectiveness is currently unknown. We hypothesize that the presence of nonneutralizing...
Autores principales: | Zhang, Pei, Wu, Charles G., Mihalik, Kathleen, Virata, Maria Luisa, Yu, Mei-ying W., Alter, Harvey J., Feinstone, Stephen M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866310/ https://www.ncbi.nlm.nih.gov/pubmed/17494735 http://dx.doi.org/10.1073/pnas.0703039104 |
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