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HIV-1 Subtype B Protease and Reverse Transcriptase Amino Acid Covariation

Despite the high degree of HIV-1 protease and reverse transcriptase (RT) mutation in the setting of antiretroviral therapy, the spectrum of possible virus variants appears to be limited by patterns of amino acid covariation. We analyzed patterns of amino acid covariation in protease and RT sequences...

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Detalles Bibliográficos
Autores principales:	Rhee, Soo-Yon, Liu, Tommy F, Holmes, Susan P, Shafer, Robert W
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866358/ https://www.ncbi.nlm.nih.gov/pubmed/17500586 http://dx.doi.org/10.1371/journal.pcbi.0030087

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