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Power of maximum HLOD tests to detect linkage to obesity genes

BACKGROUND: We investigate the power of heterogeneity LOD test to detect linkage when a trait is determined by several major genes using Genetic Analysis Workshop 13 simulated data. We consider three traits, two of which are disease-causing traits: 1) the rate of change in body mass index (BMI); and...

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Detalles Bibliográficos
Autores principales: Yoo, Yun Joo, Huo, Yanling, Ning, Yuming, Gordon, Derek, Finch, Stephen, Mendell, Nancy R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866450/
https://www.ncbi.nlm.nih.gov/pubmed/14975084
http://dx.doi.org/10.1186/1471-2156-4-S1-S16