Screening the genome to detect an association with hypertension

We report tree-based association analysis as applied to the two Framingham cohorts and to the first replication of the simulated data obtained from the Genetic Analysis Workshop 13. For this analysis, familial association is ignored. The two endpoints examined are hypertension status at initial visi...

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Detalles Bibliográficos
Autores principales: Atkinson, Elizabeth J, Andrade, Mariza de
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866501/
https://www.ncbi.nlm.nih.gov/pubmed/14975131
http://dx.doi.org/10.1186/1471-2156-4-S1-S63
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author Atkinson, Elizabeth J
Andrade, Mariza de
author_facet Atkinson, Elizabeth J
Andrade, Mariza de
author_sort Atkinson, Elizabeth J
collection PubMed
description We report tree-based association analysis as applied to the two Framingham cohorts and to the first replication of the simulated data obtained from the Genetic Analysis Workshop 13. For this analysis, familial association is ignored. The two endpoints examined are hypertension status at initial visit and time-to-hypertension, using a censored data approach. Although linkage association has previously been reported with hypertension, we found no association using the tree-based methodology.
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spelling pubmed-18665012007-05-11 Screening the genome to detect an association with hypertension Atkinson, Elizabeth J Andrade, Mariza de BMC Genet Proceedings We report tree-based association analysis as applied to the two Framingham cohorts and to the first replication of the simulated data obtained from the Genetic Analysis Workshop 13. For this analysis, familial association is ignored. The two endpoints examined are hypertension status at initial visit and time-to-hypertension, using a censored data approach. Although linkage association has previously been reported with hypertension, we found no association using the tree-based methodology. BioMed Central 2003-12-31 /pmc/articles/PMC1866501/ /pubmed/14975131 http://dx.doi.org/10.1186/1471-2156-4-S1-S63 Text en Copyright © 2003 Atkinson and Andrade; licensee BioMed Central Ltd http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Proceedings
Atkinson, Elizabeth J
Andrade, Mariza de
Screening the genome to detect an association with hypertension
title Screening the genome to detect an association with hypertension
title_full Screening the genome to detect an association with hypertension
title_fullStr Screening the genome to detect an association with hypertension
title_full_unstemmed Screening the genome to detect an association with hypertension
title_short Screening the genome to detect an association with hypertension
title_sort screening the genome to detect an association with hypertension
topic Proceedings
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866501/
https://www.ncbi.nlm.nih.gov/pubmed/14975131
http://dx.doi.org/10.1186/1471-2156-4-S1-S63
work_keys_str_mv AT atkinsonelizabethj screeningthegenometodetectanassociationwithhypertension
AT andrademarizade screeningthegenometodetectanassociationwithhypertension

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