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Importance sampling method of correction for multiple testing in affected sib-pair linkage analysis

Using the Genetic Analysis Workshop 13 simulated data set, we compared the technique of importance sampling to several other methods designed to adjust p-values for multiple testing: the Bonferroni correction, the method proposed by Feingold et al., and naïve Monte Carlo simulation. We performed aff...

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Detalles Bibliográficos
Autores principales:	Klein, Alison P, Kovac, Ilija, Sorant, Alexa JM, Baffoe-Bonnie, Agnes, Doan, Betty Q, Ibay, Grace, Lockwood, Erica, Mandal, Diptasri, Santhosh, Lekshmi, Weissbecker, Karen, Woo, Jessica, Zambelli-Weiner, April, Zhang, Jie, Naiman, Daniel Q, Malley, James, Bailey-Wilson, Joan E
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2003
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866512/ https://www.ncbi.nlm.nih.gov/pubmed/14975141 http://dx.doi.org/10.1186/1471-2156-4-S1-S73

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