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Examining the effect of linkage disequilibrium on multipoint linkage analysis

Most linkage programs assume linkage equilibrium among multiple linked markers. This assumption may lead to bias for tightly linked markers where strong linkage disequilibrium (LD) exists. We used simulated data from Genetic Analysis Workshop 14 to examine the possible effect of LD on multipoint lin...

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Detalles Bibliográficos
Autores principales:	Huang, Qiqing, Shete, Sanjay, Swartz, Michael, Amos, Christopher I
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866697/ https://www.ncbi.nlm.nih.gov/pubmed/16451698 http://dx.doi.org/10.1186/1471-2156-6-S1-S83

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