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Bias of allele-sharing linkage statistics in the presence of intermarker linkage disequilibrium
Current genome-wide linkage-mapping single-nucleotide polymorphism (SNP) panels with densities of 0.3 cM are likely to have increased intermarker linkage disequilibrium (LD) compared to 5-cM microsatellite panels. The resulting difference in haplotype frequencies versus that predicted may affect mul...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866698/ https://www.ncbi.nlm.nih.gov/pubmed/16451697 http://dx.doi.org/10.1186/1471-2156-6-S1-S82 |