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Bias of allele-sharing linkage statistics in the presence of intermarker linkage disequilibrium

Current genome-wide linkage-mapping single-nucleotide polymorphism (SNP) panels with densities of 0.3 cM are likely to have increased intermarker linkage disequilibrium (LD) compared to 5-cM microsatellite panels. The resulting difference in haplotype frequencies versus that predicted may affect mul...

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Detalles Bibliográficos
Autores principales:	Goode, Ellen L, Badzioch, Michael D, Jarvik, Gail P
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866698/ https://www.ncbi.nlm.nih.gov/pubmed/16451697 http://dx.doi.org/10.1186/1471-2156-6-S1-S82

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