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Optimizing the evidence for linkage by permuting marker order

We developed a new marker-reordering algorithm to find the best order of fine-mapping markers for multipoint linkage analysis. The algorithm searches for the best order of fine-mapping markers such that the sum of the squared differences in identity-by-descent distribution between neighboring marker...

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Detalles Bibliográficos
Autores principales: Jun, Gyungah, Song, Yeunjoo, Iyengar, Sudha K, Elston, Robert C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866721/
https://www.ncbi.nlm.nih.gov/pubmed/16451674
http://dx.doi.org/10.1186/1471-2156-6-S1-S61