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Application of a rank-based genetic association test to age-at-onset data from the Collaborative Study on the Genetics of Alcoholism study
Association studies of quantitative traits have often relied on methods in which a normal distribution of the trait is assumed. However, quantitative phenotypes from complex human diseases are often censored, highly skewed, or contaminated with outlying values. We recently developed a rank-based ass...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866730/ https://www.ncbi.nlm.nih.gov/pubmed/16451665 http://dx.doi.org/10.1186/1471-2156-6-S1-S53 |