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A gene-model-free method for linkage analysis of a disease-related-trait based on analysis of proband/sibling pairs

In this paper we investigate the power of finding linkage to a disease locus through analysis of the disease-related traits. We propose two family-based gene-model-free linkage statistics. Both involve considering the distribution of the number of alleles identical by descent with the proband and co...

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Detalles Bibliográficos
Autores principales:	Sung, Heejong, Finch, Stephen J, Ye, Kenny Q, Mendell, Nancy R
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866737/ https://www.ncbi.nlm.nih.gov/pubmed/16451658 http://dx.doi.org/10.1186/1471-2156-6-S1-S47

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