Modeling the effect of an associated single-nucleotide polymorphism in linkage studies

For linkage analysis in affected sibling pairs, we propose a regression model to incorporate information from a disease-associated single-nucleotide polymorphism located under the linkage peak. This model can be used to study if the associated single-nucleotide polymorphism marker partly explains th...

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Detalles Bibliográficos
Autores principales: Houwing-Duistermaat, Jeanine J, Uh, Hae-Won, Lebrec, Jeremie JP, Putter, Hein, Hsu, Li
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866738/
https://www.ncbi.nlm.nih.gov/pubmed/16451657
http://dx.doi.org/10.1186/1471-2156-6-S1-S46

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866738/
https://www.ncbi.nlm.nih.gov/pubmed/16451657
http://dx.doi.org/10.1186/1471-2156-6-S1-S46

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