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Modeling the effect of an associated single-nucleotide polymorphism in linkage studies
For linkage analysis in affected sibling pairs, we propose a regression model to incorporate information from a disease-associated single-nucleotide polymorphism located under the linkage peak. This model can be used to study if the associated single-nucleotide polymorphism marker partly explains th...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866738/ https://www.ncbi.nlm.nih.gov/pubmed/16451657 http://dx.doi.org/10.1186/1471-2156-6-S1-S46 |