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Local false discovery rate and minimum total error rate approaches to identifying interesting chromosomal regions
The simultaneous testing of a large number of hypotheses in a genome scan, using individual thresholds for significance, inherently leads to inflated genome-wide false positive rates. There exist various approaches to approximating the correct genomewide p-values under various assumptions, either by...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866763/ https://www.ncbi.nlm.nih.gov/pubmed/16451632 http://dx.doi.org/10.1186/1471-2156-6-S1-S23 |