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Searching for epistatic interactions in nuclear families using conditional linkage analysis

BACKGROUND: Genomic screens generally employ a single-locus strategy for linkage analysis, but this may have low power in the presence of epistasis. Ordered subsets analysis (OSA) is a method for conditional linkage analysis using continuous covariates. METHODS: We used OSA to evaluate two-locus int...

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Detalles Bibliográficos
Autores principales:	Shah, Svati H, Schmidt, Michael A, Mei, Hao, Scott, William K, Hauser, Elizabeth R, Schmidt, Silke
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866787/ https://www.ncbi.nlm.nih.gov/pubmed/16451608 http://dx.doi.org/10.1186/1471-2156-6-S1-S148

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