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Multifactor-dimensionality reduction versus family-based association tests in detecting susceptibility loci in discordant sib-pair studies
Complex diseases are generally thought to be under the influence of multiple, and possibly interacting, genes. Many association methods have been developed to identify susceptibility genes assuming a single-gene disease model, referred to as single-locus methods. Multilocus methods consider joint ef...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866789/ https://www.ncbi.nlm.nih.gov/pubmed/16451606 http://dx.doi.org/10.1186/1471-2156-6-S1-S146 |