Smoothing of the bivariate LOD score for non-normal quantitative traits

Variance component analysis provides an efficient method for performing linkage analysis for quantitative traits. However, type I error of variance components-based likelihood ratio testing may be affected when phenotypic data are non-normally distributed (especially with high values of kurtosis). T...

Descripción completa

Detalles Bibliográficos
Autores principales: Buil, Alfonso, Dyer, Thomas D, Almasy, Laura, Blangero, John
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866827/
https://www.ncbi.nlm.nih.gov/pubmed/16451568
http://dx.doi.org/10.1186/1471-2156-6-S1-S111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866827/
https://www.ncbi.nlm.nih.gov/pubmed/16451568
http://dx.doi.org/10.1186/1471-2156-6-S1-S111

Ejemplares similares