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How to quantify information loss due to phase ambiguity in haplotype case-control studies
Assigning haplotypes in a case-control study is a challenging problem. We proposed a method to quantify the information loss due to missing phase information. We determined which individuals were responsible for the information loss, and calculated how much information could be gained when the ambig...
Autores principales: | Uh, Hae-Won, Houwing-Duistermaat, Jeanine J, Putter, Hein, van Houwelingen, Hans C |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866831/ https://www.ncbi.nlm.nih.gov/pubmed/16451564 http://dx.doi.org/10.1186/1471-2156-6-S1-S108 |
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