Methods to test for association between a disease and a multi-allelic marker applied to a candidate region

We report the analysis results of the Genetic Analysis Workshop 14 simulated microsatellite marker dataset, using replicate 50 from the Danacaa population. We applied several methods for association analysis of multi-allelic markers to case-control data to study the association between Kofendrerd Pe...

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Detalles Bibliográficos
Autores principales: El Galta, Rachid, Hsu, Li, Houwing-Duistermaat, Jeanine J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866838/
https://www.ncbi.nlm.nih.gov/pubmed/16451557
http://dx.doi.org/10.1186/1471-2156-6-S1-S101
Descripción
Sumario:We report the analysis results of the Genetic Analysis Workshop 14 simulated microsatellite marker dataset, using replicate 50 from the Danacaa population. We applied several methods for association analysis of multi-allelic markers to case-control data to study the association between Kofendrerd Personality Disorder and multi-allelic markers in a candidate region previously identified by the linkage analysis. Evidence for association was found for marker D03S0127 (p < 0.01). The analyses were done without any prior knowledge of the answers.

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