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Deletion of IL-4Rα on CD4 T Cells Renders BALB/c Mice Resistant to Leishmania major Infection

Effector responses induced by polarized CD4(+) T helper 2 (Th2) cells drive nonhealing responses in BALB/c mice infected with Leishmania major. Th2 cytokines IL-4 and IL-13 are known susceptibility factors for L. major infection in BALB/c mice and induce their biological functions through a common r...

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Detalles Bibliográficos
Autores principales:	Radwanska, Magdalena, Cutler, Antony J, Hoving, J. Claire, Magez, Stefan, Holscher, Christoph, Bohms, Andreas, Arendse, Berenice, Kirsch, Richard, Hunig, Thomas, Alexander, James, Kaye, Paul, Brombacher, Frank
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1867380/ https://www.ncbi.nlm.nih.gov/pubmed/17500591 http://dx.doi.org/10.1371/journal.ppat.0030068

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