Inhibition of the alternative complement activation pathway in traumatic brain injury by a monoclonal anti-factor B antibody: a randomized placebo-controlled study in mice

BACKGROUND: The posttraumatic response to traumatic brain injury (TBI) is characterized, in part, by activation of the innate immune response, including the complement system. We have recently shown that mice devoid of a functional alternative pathway of complement activation (factor B-/- mice) are...

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Detalles Bibliográficos
Autores principales: Leinhase, Iris, Rozanski, Michal, Harhausen, Denise, Thurman, Joshua M, Schmidt, Oliver I, Hossini, Amir M, Taha, Mohy E, Rittirsch, Daniel, Ward, Peter A, Holers, V Michael, Ertel, Wolfgang, Stahel, Philip F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1867808/
https://www.ncbi.nlm.nih.gov/pubmed/17474994
http://dx.doi.org/10.1186/1742-2094-4-13

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