Atrazine-Induced Aromatase Expression Is SF-1 Dependent: Implications for Endocrine Disruption in Wildlife and Reproductive Cancers in Humans

BACKGROUND: Atrazine is a potent endocrine disruptor that increases aromatase expression in some human cancer cell lines. The mechanism involves the inhibition of phosphodiesterase and subsequent elevation of cAMP. METHODS: We compared steroidogenic factor 1 (SF-1) expression in atrazine responsive...

Descripción completa

Detalles Bibliográficos
Autores principales: Fan, WuQiang, Yanase, Toshihiko, Morinaga, Hidetaka, Gondo, Shigeki, Okabe, Taijiro, Nomura, Masatoshi, Komatsu, Tomoko, Morohashi, Ken-Ichirou, Hayes, Tyrone B., Takayanagi, Ryoichi, Nawata, Hajime
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1867956/
https://www.ncbi.nlm.nih.gov/pubmed/17520059
http://dx.doi.org/10.1289/ehp.9758

Ejemplares similares

Ejemplares similares