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Concurrent pulmonary zygomycosis and Mycobacterium tuberculosis infection: a case report
A non-smoking 77-year old gentleman of Indian origin was admitted with a 4-month history of intermittent night sweats, haemoptysis and 6 kg of weight loss. CT scan of thorax demonstrated a 2.5 cm mass in the right middle lobe with multiple small nodules within the right lung and confirmed the presen...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868082/ https://www.ncbi.nlm.nih.gov/pubmed/17477864 http://dx.doi.org/10.1186/1752-1947-1-17 |
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author | Patel, Tejal Clifton, Ian J Kastelik, Jack A Peckham, Daniel G |
author_facet | Patel, Tejal Clifton, Ian J Kastelik, Jack A Peckham, Daniel G |
author_sort | Patel, Tejal |
collection | PubMed |
description | A non-smoking 77-year old gentleman of Indian origin was admitted with a 4-month history of intermittent night sweats, haemoptysis and 6 kg of weight loss. CT scan of thorax demonstrated a 2.5 cm mass in the right middle lobe with multiple small nodules within the right lung and confirmed the presence of mediastinal and hilar lymph nodes. Fibreoptic bronchoscopy demonstrated a distorted right main bronchus, anterior shift of the right upper lobe and occlusion of the right middle lobe bronchus with a black necrotic ulcer. Mycobacterium tuberculosis was found in the bronchoalveolar lavage and histology demonstrated numerous fungal hyphae with a morphological appearance of zygomycetes within necrotic areas of tissue. Medical management with anti-fungal and anti-mycobacterial treatment was instigated as the patient's pre-existing IHD did not permit surgical intervention. Subsequently CT imaging following completion of therapy demonstrated improvement of the mass and a resolution of the associated nodules. The patient has been followed for 6 months to date and there has been no recurrence of symptoms. Recent bronchoalveolar lavage cultures have been negative for M. tuberculosis and zygomycetes. |
format | Text |
id | pubmed-1868082 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2007 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-18680822007-05-14 Concurrent pulmonary zygomycosis and Mycobacterium tuberculosis infection: a case report Patel, Tejal Clifton, Ian J Kastelik, Jack A Peckham, Daniel G J Med Case Reports Case Report A non-smoking 77-year old gentleman of Indian origin was admitted with a 4-month history of intermittent night sweats, haemoptysis and 6 kg of weight loss. CT scan of thorax demonstrated a 2.5 cm mass in the right middle lobe with multiple small nodules within the right lung and confirmed the presence of mediastinal and hilar lymph nodes. Fibreoptic bronchoscopy demonstrated a distorted right main bronchus, anterior shift of the right upper lobe and occlusion of the right middle lobe bronchus with a black necrotic ulcer. Mycobacterium tuberculosis was found in the bronchoalveolar lavage and histology demonstrated numerous fungal hyphae with a morphological appearance of zygomycetes within necrotic areas of tissue. Medical management with anti-fungal and anti-mycobacterial treatment was instigated as the patient's pre-existing IHD did not permit surgical intervention. Subsequently CT imaging following completion of therapy demonstrated improvement of the mass and a resolution of the associated nodules. The patient has been followed for 6 months to date and there has been no recurrence of symptoms. Recent bronchoalveolar lavage cultures have been negative for M. tuberculosis and zygomycetes. BioMed Central 2007-05-03 /pmc/articles/PMC1868082/ /pubmed/17477864 http://dx.doi.org/10.1186/1752-1947-1-17 Text en Copyright © 2007 Patel et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Patel, Tejal Clifton, Ian J Kastelik, Jack A Peckham, Daniel G Concurrent pulmonary zygomycosis and Mycobacterium tuberculosis infection: a case report |
title | Concurrent pulmonary zygomycosis and Mycobacterium tuberculosis infection: a case report |
title_full | Concurrent pulmonary zygomycosis and Mycobacterium tuberculosis infection: a case report |
title_fullStr | Concurrent pulmonary zygomycosis and Mycobacterium tuberculosis infection: a case report |
title_full_unstemmed | Concurrent pulmonary zygomycosis and Mycobacterium tuberculosis infection: a case report |
title_short | Concurrent pulmonary zygomycosis and Mycobacterium tuberculosis infection: a case report |
title_sort | concurrent pulmonary zygomycosis and mycobacterium tuberculosis infection: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868082/ https://www.ncbi.nlm.nih.gov/pubmed/17477864 http://dx.doi.org/10.1186/1752-1947-1-17 |
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