Screening of the transcriptional regulatory regions of vascular endothelial growth factor receptor 2 (VEGFR2) in amyotrophic lateral sclerosis

BACKGROUND: Vascular endothelial growth factor (VEGF) has neurotrophic activity which is mediated by its main agonist receptor, VEGFR2. Dysregulation of VEGF causes motor neurone degeneration in a mouse model of amyotrophic lateral sclerosis (ALS), and expression of VEGFR2 is reduced in motor neuron...

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Detalles Bibliográficos
Autores principales: Brockington, Alice, Wokke, Beatrijs, Nixon, Hannah, Hartley, Judith, Shaw, Pamela J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868706/
https://www.ncbi.nlm.nih.gov/pubmed/17456229
http://dx.doi.org/10.1186/1471-2350-8-23

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