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Gene transfer of wild-type apoA-I and apoA-I Milano reduce atherosclerosis to a similar extent

BACKGROUND: The atheroprotective effects of systemic delivery of either apolipoprotein A-I (wtApoA-I) or the naturally occurring mutant ApoA-I Milano (ApoA-I(M)) have been established in animal and human trials, but direct comparison studies evaluating the phenotype of ApoA-I or ApoAI-Milano knock-i...

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Detalles Bibliográficos
Autores principales: Lebherz, Corinna, Sanmiguel, Julio, Wilson, James M, Rader, Daniel J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868709/
https://www.ncbi.nlm.nih.gov/pubmed/17475009
http://dx.doi.org/10.1186/1475-2840-6-15