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Gene transfer of wild-type apoA-I and apoA-I Milano reduce atherosclerosis to a similar extent
BACKGROUND: The atheroprotective effects of systemic delivery of either apolipoprotein A-I (wtApoA-I) or the naturally occurring mutant ApoA-I Milano (ApoA-I(M)) have been established in animal and human trials, but direct comparison studies evaluating the phenotype of ApoA-I or ApoAI-Milano knock-i...
Autores principales: | Lebherz, Corinna, Sanmiguel, Julio, Wilson, James M, Rader, Daniel J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868709/ https://www.ncbi.nlm.nih.gov/pubmed/17475009 http://dx.doi.org/10.1186/1475-2840-6-15 |
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