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Phenotype and in vitro function of mature MDDC generated from cryopreserved PBMC of cancer patients are equivalent to those from healthy donors
BACKGROUND: Monocyte-derived-dendritic-cells (MDDC) are the major DC type used in vaccine-based clinical studies for a variety of cancers. In order to assess whether in vitro differentiated MDDC from cryopreserved PBMC of cancer patients are functionally distinct from those of healthy donors, we com...
Autores principales: | Ghanekar, Smita A, Bhatia, Sonny, Ruitenberg, Joyce J, Rosa, Corazon DeLa, Disis, Mary L, Maino, Vernon C, Maecker, Holden T, Waters, Cory A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868730/ https://www.ncbi.nlm.nih.gov/pubmed/17477875 http://dx.doi.org/10.1186/1476-8518-5-7 |
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