Cargando…

A multimodality localization technique for radio-guided surgery

BACKGROUND: Intraoperative localization of image or endoscopy-detected lesions occasionally pose surgical challenges due to the small lesion size and/or difficult anatomic exposure. Identification of such lesions can be facilitated using a hand-held gamma probe with utilization of Tc-99m macroaggreg...

Descripción completa

Detalles Bibliográficos
Autores principales: Gulec, Seza A, Hoenie, Erica, Rheinheimer, Kristan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868731/
https://www.ncbi.nlm.nih.gov/pubmed/17459152
http://dx.doi.org/10.1186/1477-7819-5-43
_version_ 1782133392962224128
author Gulec, Seza A
Hoenie, Erica
Rheinheimer, Kristan
author_facet Gulec, Seza A
Hoenie, Erica
Rheinheimer, Kristan
author_sort Gulec, Seza A
collection PubMed
description BACKGROUND: Intraoperative localization of image or endoscopy-detected lesions occasionally pose surgical challenges due to the small lesion size and/or difficult anatomic exposure. Identification of such lesions can be facilitated using a hand-held gamma probe with utilization of Tc-99m macroaggregate albumen (MAA) localization technique. The radiopharmaceutical injection can be performed using ultrasound (US) or endoscopy guidance. CASE PRESENTATIONS: The clinical use of the Tc-99m MAA protocol gamma probe-guided surgery was discussed in three representative cases. Surgical indication was diagnostic exploration in two patients with suspicious lymphadenopathy, and determination of extent of surgical resection in a patient with polyposis. Lesion localization with 100 microcurie (3.7 MBq) Tc-99m MAA prior to surgical exploration resulted in definitive localization of lesions intraoperatively. CONCLUSION: The use Tc-99m MAA deposition technique at the site of surgical target is a highly efficient radio-guided surgery technique with definitive impact on the success of surgical exploration in selected indications.
format Text
id pubmed-1868731
institution National Center for Biotechnology Information
language English
publishDate 2007
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-18687312007-05-15 A multimodality localization technique for radio-guided surgery Gulec, Seza A Hoenie, Erica Rheinheimer, Kristan World J Surg Oncol Technical Innovations BACKGROUND: Intraoperative localization of image or endoscopy-detected lesions occasionally pose surgical challenges due to the small lesion size and/or difficult anatomic exposure. Identification of such lesions can be facilitated using a hand-held gamma probe with utilization of Tc-99m macroaggregate albumen (MAA) localization technique. The radiopharmaceutical injection can be performed using ultrasound (US) or endoscopy guidance. CASE PRESENTATIONS: The clinical use of the Tc-99m MAA protocol gamma probe-guided surgery was discussed in three representative cases. Surgical indication was diagnostic exploration in two patients with suspicious lymphadenopathy, and determination of extent of surgical resection in a patient with polyposis. Lesion localization with 100 microcurie (3.7 MBq) Tc-99m MAA prior to surgical exploration resulted in definitive localization of lesions intraoperatively. CONCLUSION: The use Tc-99m MAA deposition technique at the site of surgical target is a highly efficient radio-guided surgery technique with definitive impact on the success of surgical exploration in selected indications. BioMed Central 2007-04-25 /pmc/articles/PMC1868731/ /pubmed/17459152 http://dx.doi.org/10.1186/1477-7819-5-43 Text en Copyright © 2007 Gulec et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Technical Innovations
Gulec, Seza A
Hoenie, Erica
Rheinheimer, Kristan
A multimodality localization technique for radio-guided surgery
title A multimodality localization technique for radio-guided surgery
title_full A multimodality localization technique for radio-guided surgery
title_fullStr A multimodality localization technique for radio-guided surgery
title_full_unstemmed A multimodality localization technique for radio-guided surgery
title_short A multimodality localization technique for radio-guided surgery
title_sort multimodality localization technique for radio-guided surgery
topic Technical Innovations
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868731/
https://www.ncbi.nlm.nih.gov/pubmed/17459152
http://dx.doi.org/10.1186/1477-7819-5-43
work_keys_str_mv AT gulecsezaa amultimodalitylocalizationtechniqueforradioguidedsurgery
AT hoenieerica amultimodalitylocalizationtechniqueforradioguidedsurgery
AT rheinheimerkristan amultimodalitylocalizationtechniqueforradioguidedsurgery
AT gulecsezaa multimodalitylocalizationtechniqueforradioguidedsurgery
AT hoenieerica multimodalitylocalizationtechniqueforradioguidedsurgery
AT rheinheimerkristan multimodalitylocalizationtechniqueforradioguidedsurgery