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Glucocorticoids activate TGF-β induced PAI-1 and CTGF expression in rat hepatocytes

BACKGROUND: In addition to the activation of hepatic stellate cells TGF-β govern apoptosis and growth control of hepatocytes in liver injury. In non-parenchymal cells, TGF-β induces plasminogen activator inhibitor 1 (PAI-1) and connective tissue growth factor (CTGF) expression, which are involved in...

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Detalles Bibliográficos
Autores principales:	Wickert, Lucia, Chatain, Nicolas, Kruschinsky, Karin, Gressner, Axel M
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868771/ https://www.ncbi.nlm.nih.gov/pubmed/17474984 http://dx.doi.org/10.1186/1476-5926-6-5

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