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A First Look at ARFome: Dual-Coding Genes in Mammalian Genomes

Coding of multiple proteins by overlapping reading frames is not a feature one would associate with eukaryotic genes. Indeed, codependency between codons of overlapping protein-coding regions imposes a unique set of evolutionary constraints, making it a costly arrangement. Yet in cases of tightly co...

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Detalles Bibliográficos
Autores principales: Chung, Wen-Yu, Wadhawan, Samir, Szklarczyk, Radek, Pond, Sergei Kosakovsky, Nekrutenko, Anton
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868773/
https://www.ncbi.nlm.nih.gov/pubmed/17511511
http://dx.doi.org/10.1371/journal.pcbi.0030091