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Genomic tagging of endogenous Type IIβ Phosphatidylinositol 5-phosphate 4-kinase in DT40 cells reveals a nuclear localisation

Previous studies from acutely transfected HeLa cells have identified an acidic α-helix in the Type IIβ PtdIns5P 4-kinase (PIPkin IIβ) as a putative novel nuclear localisation sequence (Ciruela et al. Biochem. J. 364, 587–591 2000). However, some heterogeneity in cellular localisation was always obse...

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Detalles Bibliográficos
Autores principales: Richardson, Jonathan P., Wang, Minchuan, Clarke, Jonathan H., Patel, Ketan J., Irvine, R.F.
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868964/
https://www.ncbi.nlm.nih.gov/pubmed/17303380
http://dx.doi.org/10.1016/j.cellsig.2007.01.010