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Requirement of aggregation propensity of Alzheimer amyloid peptides for neuronal cell surface binding
BACKGROUND: Aggregation of the amyloid peptides, Aβ40 and Aβ42, is known to be involved in the pathology of Alzheimer's disease (AD). Here we investigate the relationship between peptide aggregation and cell surface binding of three forms of Aβ (Aβ40, Aβ42, and an Aβ mutant). RESULTS: Using con...
Autores principales: | Bateman, David A, McLaurin, JoAnne, Chakrabartty, Avijit |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1871596/ https://www.ncbi.nlm.nih.gov/pubmed/17475015 http://dx.doi.org/10.1186/1471-2202-8-29 |
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