Methylation-sensitive high resolution melting (MS-HRM): a new approach for sensitive and high-throughput assessment of methylation

In this article, we show that high resolution melting analysis (HRM) is a sensitive and specific method for the detection of methylation. Methylated DNA and unmethylated DNA acquire different sequences after bisulphite treatment resulting in PCR products with markedly different melting profiles. We...

Descripción completa

Detalles Bibliográficos
Autores principales: Wojdacz, Tomasz K., Dobrovic, Alexander
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874596/
https://www.ncbi.nlm.nih.gov/pubmed/17289753
http://dx.doi.org/10.1093/nar/gkm013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874596/
https://www.ncbi.nlm.nih.gov/pubmed/17289753
http://dx.doi.org/10.1093/nar/gkm013

Ejemplares similares