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Methylation-sensitive high resolution melting (MS-HRM): a new approach for sensitive and high-throughput assessment of methylation

In this article, we show that high resolution melting analysis (HRM) is a sensitive and specific method for the detection of methylation. Methylated DNA and unmethylated DNA acquire different sequences after bisulphite treatment resulting in PCR products with markedly different melting profiles. We...

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Detalles Bibliográficos
Autores principales:	Wojdacz, Tomasz K., Dobrovic, Alexander
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2007
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874596/ https://www.ncbi.nlm.nih.gov/pubmed/17289753 http://dx.doi.org/10.1093/nar/gkm013

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