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Mechanism of the formation of DNA–protein cross-links by antitumor cisplatin

DNA–protein cross-links are formed by various DNA-damaging agents including antitumor platinum drugs. The natures of these ternary DNA–Pt–protein complexes (DPCLs) can be inferred, yet much remains to be learned about their structures and mechanisms of formation. We investigated the origin of these...

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Detalles Bibliográficos
Autores principales:	Chválová, Kateřina, Brabec, Viktor, Kašpárková, Jana
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2007
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874601/ https://www.ncbi.nlm.nih.gov/pubmed/17329374 http://dx.doi.org/10.1093/nar/gkm032

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