The protein that binds to DNA base J in trypanosomatids has features of a thymidine hydroxylase

Trypanosomatids contain an unusual DNA base J (β-d-glucosylhydroxymethyluracil), which replaces a fraction of thymine in telomeric and other DNA repeats. To determine the function of base J, we have searched for enzymes that catalyze J biosynthesis. We present evidence that a protein that binds to J...

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Detalles Bibliográficos
Autores principales: Yu, Zhong, Genest, Paul-André, ter Riet, Bas, Sweeney, Kate, DiPaolo, Courtney, Kieft, Rudo, Christodoulou, Evangelos, Perrakis, Anastassis, Simmons, Jana M., Hausinger, Robert P., van Luenen, Henri G.A.M., Rigden, Daniel J., Sabatini, Robert, Borst, Piet
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874643/
https://www.ncbi.nlm.nih.gov/pubmed/17389644
http://dx.doi.org/10.1093/nar/gkm049

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