Cargando…

Transactivation of a DR-1 PPRE by a human constitutive androstane receptor variant expressed from internal protein translation start sites

Downstream in-frame start codons produce amino-terminal-truncated human constitutive androstane receptor protein isoforms (ΔNCARs). The ΔNCARs are expressed in liver and in vitro cell systems following translation from in-frame methionine AUG start codons at positions 76, 80, 125, 128, 168 and 265 w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Stoner, Matthew A., Auerbach, Scott S., Zamule, Stephanie M., Strom, Stephen C., Omiecinski, Curtis J.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2007
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874654/ https://www.ncbi.nlm.nih.gov/pubmed/17355985 http://dx.doi.org/10.1093/nar/gkm090

Ejemplares similares

Constitutive androstane receptor 1 is constitutively bound to chromatin and ‘primed’ for transactivation in hepatocytes
por: McMahon, Michael, et al.
Publicado: (2019)

In vivo genome-wide binding interactions of mouse and human constitutive androstane receptors reveal novel gene targets
por: Niu, Ben, et al.
Publicado: (2018)

Transactivation Assays to Assess Canine and Rodent Pregnane X Receptor (PXR) and Constitutive Androstane Receptor (CAR) Activation
por: Pinne, Marija, et al.
Publicado: (2016)

Signaling control of the constitutive androstane receptor (CAR)
por: Yang, Hui, et al.
Publicado: (2014)

Noncanonical Constitutive Androstane Receptor Signaling in Gene Regulation
por: Pustylnyak, Yuliya A., et al.
Publicado: (2020)

Metabolism-Disrupting Chemicals and the Constitutive Androstane Receptor CAR
por: Küblbeck, Jenni, et al.
Publicado: (2020)

β-catenin signaling, the constitutive androstane receptor and their mutual interactions
por: Braeuning, Albert, et al.
Publicado: (2020)

Studies of Coumarin Derivatives for Constitutive Androstane Receptor (CAR) Activation
por: Juang, Shin-Hun, et al.
Publicado: (2020)

Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor
por: Lukowicz, Céline, et al.
Publicado: (2019)

Activation of the Constitutive Androstane Receptor Inhibits Leukocyte Adhesiveness to Dysfunctional Endothelium
por: López-Riera, Mireia, et al.
Publicado: (2021)

SAT017 Investigating The Spatial Regulation Mediated By Constitutive Androstane Receptor
por: Asokakumar, Anjana, et al.
Publicado: (2023)

Quantitative High-Throughput Identification of Drugs as Modulators of Human Constitutive Androstane Receptor
por: Lynch, Caitlin, et al.
Publicado: (2015)

Constitutive Androstane Receptor: A Peripheral and a Neurovascular Stress or Environmental Sensor
por: Oliviero, Fabiana, et al.
Publicado: (2020)

Alternative splicing affects the function and tissue-specific expression of the human constitutive androstane receptor
por: Arnold, Katja A, et al.
Publicado: (2004)

Nigramide J is a novel potent inverse agonist of the human constitutive androstane receptor
por: Kanno, Yuichiro, et al.
Publicado: (2014)

Structural and Functional Similarity of Amphibian Constitutive Androstane Receptor with Mammalian Pregnane X Receptor
por: Mathäs, Marianne, et al.
Publicado: (2014)

Effects of Pioglitazone on Nonalcoholic Fatty Liver Disease in the Absence of Constitutive Androstane Receptor Expression
por: Ahn, Hwa Young, et al.
Publicado: (2018)

Author Correction: Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor
por: Lukowicz, Céline, et al.
Publicado: (2020)

Deletion of Constitutive Androstane Receptor Led to Intestinal Alterations and Increased Imidacloprid in Murine Liver
por: Sen, Anushna, et al.
Publicado: (2022)

Computational identification and experimental validation of PPRE motifs in NHE1 and MnSOD genes of Human
por: Venkatachalam, Gireedhar, et al.
Publicado: (2009)

MicroRNA-122 Down-Regulation Is Involved in Phenobarbital-Mediated Activation of the Constitutive Androstane Receptor
por: Shizu, Ryota, et al.
Publicado: (2012)

Constitutive androstane receptor agonist CITCO inhibits growth and expansion of brain tumour stem cells
por: Chakraborty, S, et al.
Publicado: (2011)

Correction: Structural and Functional Similarity of Amphibian Constitutive Androstane Receptor with Mammalian Pregnane X Receptor
Publicado: (2014)

Correction: Structural and Functional Similarity of Amphibian Constitutive Androstane Receptor with Mammalian Pregnane X Receptor
por: Mathäs, Marianne, et al.
Publicado: (2016)

Constitutive Androstane Receptor Differentially Regulates Bile Acid Homeostasis in Mouse Models of Intrahepatic Cholestasis
por: Kim, Kang Ho, et al.
Publicado: (2018)

Gadd45b is required in part for the anti-obesity effect of constitutive androstane receptor (CAR)
por: Cai, Xinran, et al.
Publicado: (2021)

Deletion of Nuclear Receptor Constitutive Androstane Receptor CAR Increases Anxiety and Lowers Androgen Levels
por: Hernandez, Juan P, et al.
Publicado: (2021)

RF03 | PMON287 Examining the role of Constitutive Androstane Receptor during Imidacloprid exposure
por: Sen, Anushna, et al.
Publicado: (2022)

The antibiotic Furvina® targets the P-site of 30S ribosomal subunits and inhibits translation initiation displaying start codon bias
por: Fabbretti, Attilio, et al.
Publicado: (2012)

CYP1A1 Induction in the Colon by Serum: Involvement of the PPARα Pathway and Evidence for a New Specific Human PPREα Site
por: Villard, Pierre-Henri, et al.
Publicado: (2011)

Triclocarban Mediates Induction of Xenobiotic Metabolism through Activation of the Constitutive Androstane Receptor and the Estrogen Receptor Alpha
por: Yueh, Mei-Fei, et al.
Publicado: (2012)

Correction: MicroRNA-122 Down-Regulation Is Involved in Phenobarbital-Mediated Activation of the Constitutive Androstane Receptor
por: Shizu, Ryota, et al.
Publicado: (2013)

A Targeted in Vivo SILAC Approach for Quantification of Drug Metabolism Enzymes: Regulation by the Constitutive Androstane Receptor
por: MacLeod, A. Kenneth, et al.
Publicado: (2013)

Functional constraints on the constitutive androstane receptor inferred from human sequence variation and cross-species comparisons
por: Thompson, Emma E, et al.
Publicado: (2005)

Constitutive androstane receptor activation promotes bilirubin clearance in a murine model of alcoholic liver disease
por: Wang, Xiuyan, et al.
Publicado: (2017)

Antiproliferation of berberine is mediated by epigenetic modification of constitutive androstane receptor (CAR) metabolic pathway in hepatoma cells
por: Zhang, Lei, et al.
Publicado: (2016)

Transcriptomic analysis across liver diseases reveals disease-modulating activation of constitutive androstane receptor in cholestasis
por: Mathur, Bhoomika, et al.
Publicado: (2020)

Constitutive androstane receptor induced-hepatomegaly and liver regeneration is partially via yes-associated protein activation
por: Gao, Yue, et al.
Publicado: (2021)

Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure
por: Mejdrová, Ivana, et al.
Publicado: (2023)

Constitutive Androstane Receptor Agonist, TCPOBOP: Maternal Exposure Impairs the Growth and Development of Female Offspring in Mice
por: Pan, Shijia, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_oljmvrguuf8pqkoocmfarao44c