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The Deuterator: software for the determination of backbone amide deuterium levels from H/D exchange MS data

BACKGROUND: The combination of mass spectrometry and solution phase amide hydrogen/deuterium exchange (H/D exchange) experiments is an effective method for characterizing protein dynamics, and protein-protein or protein-ligand interactions. Despite methodological advancements and improvements in ins...

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Detalles Bibliográficos
Autores principales: Pascal, BD, Chalmers, MJ, Busby, SA, Mader, CC, Southern, MR, Tsinoremas, NF, Griffin, PR
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1876250/
https://www.ncbi.nlm.nih.gov/pubmed/17506883
http://dx.doi.org/10.1186/1471-2105-8-156

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