LEDGF/p75 has increased expression in blasts from chemotherapy-resistant human acute myelogenic leukemia patients and protects leukemia cells from apoptosis in vitro

BACKGROUND: Relapse due to chemoresistant residual disease is a major cause of death in acute myelogenous leukemia (AML). The present study was undertaken to elucidate the molecular mechanisms of chemoresistance by comparing differential gene expression in blasts from patients with resistant relapsi...

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Detalles Bibliográficos
Autores principales: Huang, Tien-sheng, Myklebust, Line M, Kjarland, Endre, Gjertsen, Bjørn Tore, Pendino, Frederic, Bruserud, Øystein, Døskeland, Stein Ove, Lillehaug, Johan R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1876472/
https://www.ncbi.nlm.nih.gov/pubmed/17451600
http://dx.doi.org/10.1186/1476-4598-6-31

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