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Molecular Dynamics of Retinoic Acid-Induced Craniofacial Malformations: Implications for the Origin of Gnathostome Jaws

BACKGROUND: Intake of retinoic acid (RA) or of its precursor, vitamin A, during early pregnancy is associated with increased incidence of craniofacial lesions. The origin of these teratogenic effects remains enigmatic as in cranial neural crest cells (CNCCs), which largely contribute to craniofacial...

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Detalles Bibliográficos
Autores principales: Vieux-Rochas, Maxence, Coen, Laurent, Sato, Takahiro, Kurihara, Yukiko, Gitton, Yorick, Barbieri, Ottavia, Blay, Karine Le, Merlo, Giorgio, Ekker, Marc, Kurihara, Hiroki, Janvier, Philippe, Levi, Giovanni
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1876820/
https://www.ncbi.nlm.nih.gov/pubmed/17551590
http://dx.doi.org/10.1371/journal.pone.0000510

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