Promoter methylation of RASSF1A and DAPK and mutations of K-ras, p53, and EGFR in lung tumors from smokers and never-smokers

BACKGROUND: Epidemiological studies indicate that some characteristics of lung cancer among never-smokers significantly differ from those of smokers. Aberrant promoter methylation and mutations in some oncogenes and tumor suppressor genes are frequent in lung tumors from smokers but rare in those fr...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Gao, Weimin, Siegfried, Jill M, Weissfeld, Joel L, Luketich, James D, Keohavong, Phouthone
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1877812/
https://www.ncbi.nlm.nih.gov/pubmed/17477876
http://dx.doi.org/10.1186/1471-2407-7-74

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