IFNG +874T/A polymorphism is not associated with American tegumentary leishmaniasis susceptibility but can influence Leishmania induced IFN-γ production

BACKGROUND: Interferon-gamma is a key cytokine in the protective responses against intracellular pathogens. A single nucleotide polymorphism (SNP) located in the first intron of the human IFN-γ gene can putatively influence the secretion of cytokine with an impact on infection outcome as demonstrate...

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Detalles Bibliográficos
Autores principales: Matos, Guilherme Inocêncio, Covas, Claudia de J Fernandes, Bittar, Rita de Cássia, Gomes-Silva, Adriano, Marques, Fabiana, Maniero, Viviane C, Amato, Valdir S, Oliveira-Neto, Manoel P, Mattos, Marise da Silva, Pirmez, Claude, Sampaio, Elizabeth P, Moraes, Milton O, Da-Cruz, Alda Maria
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1878480/
https://www.ncbi.nlm.nih.gov/pubmed/17456233
http://dx.doi.org/10.1186/1471-2334-7-33

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