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Prophylactic and Therapeutic Efficacy of Human Monoclonal Antibodies against H5N1 Influenza

BACKGROUND: New prophylactic and therapeutic strategies to combat human infections with highly pathogenic avian influenza (HPAI) H5N1 viruses are needed. We generated neutralizing anti-H5N1 human monoclonal antibodies (mAbs) and tested their efficacy for prophylaxis and therapy in a murine model of...

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Detalles Bibliográficos
Autores principales:	Simmons, Cameron P, Bernasconi, Nadia L, Suguitan, Amorsolo L, Mills, Kimberly, Ward, Jerrold M, Chau, Nguyen Van Vinh, Hien, Tran Tinh, Sallusto, Federica, Ha, Do Quang, Farrar, Jeremy, de Jong, Menno D, Lanzavecchia, Antonio, Subbarao, Kanta
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1880850/ https://www.ncbi.nlm.nih.gov/pubmed/17535101 http://dx.doi.org/10.1371/journal.pmed.0040178

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