Cargando…
In Vivo Expression Pattern of MICA and MICB and Its Relevance to Auto-Immunity and Cancer
Non-conventional MHC class I MIC molecules interact not with the TCR, but with NKG2D, a C-type lectin activatory receptor present on most NK, γδ and CD8(+) αβ T cells. While this interaction is critical in triggering/calibrating the cytotoxic activity of these cells, the actual extent of its in vivo...
| Autores principales: | , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2007
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885219/ https://www.ncbi.nlm.nih.gov/pubmed/17565371 http://dx.doi.org/10.1371/journal.pone.0000518 |