Cargando…

Purification and preliminary crystallization of alanine racemase from Streptococcus pneumoniae

BACKGROUND: Over the past fifteen years, antibiotic resistance in the Gram-positive opportunistic human pathogen Streptococcus pneumoniae has significantly increased. Clinical isolates from patients with community-acquired pneumonia or otitis media often display resistance to two or more antibiotics...

Descripción completa

Detalles Bibliográficos
Autores principales:	Strych, Ulrich, Davlieva, Milya, Longtin, Joseph P, Murphy, Eileen L, Im, Hookang, Benedik, Michael J, Krause, Kurt L
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885262/ https://www.ncbi.nlm.nih.gov/pubmed/17509154 http://dx.doi.org/10.1186/1471-2180-7-40

Ejemplares similares

The crystal structure of alanine racemase from Streptococcus pneumoniae, a target for structure-based drug design
por: Im, Hookang, et al.
Publicado: (2011)

Biochemical and structural characterization of alanine racemase from Bacillus anthracis (Ames)
por: Couñago, Rafael M, et al.
Publicado: (2009)

Purification, Characterization and Inhibition of Alanine Racemase from a Pathogenic Strain of Streptococcus iniae
por: MUHAMMAD, MURTALA, et al.
Publicado: (2019)

The structure of alanine racemase from Acinetobacter baumannii
por: Davis, Emily, et al.
Publicado: (2014)

New Classes of Alanine Racemase Inhibitors Identified by High-Throughput Screening Show Antimicrobial Activity against Mycobacterium tuberculosis
por: Anthony, Karen G., et al.
Publicado: (2011)

Alanine racemase is essential for the growth and interspecies competitiveness of Streptococcus mutans
por: Wei, Yuan, et al.
Publicado: (2016)

Function of alanine racemase in the physiological activity and cariogenicity of Streptococcus mutans
por: Liu, Shiyu, et al.
Publicado: (2018)

Structural features and kinetic characterization of alanine racemase from Staphylococcus aureus (Mu50)
por: Scaletti, Emma R., et al.
Publicado: (2012)

Alanine Racemase Mutants of Burkholderia pseudomallei and Burkholderia mallei and Use of Alanine Racemase as a Non-Antibiotic-Based Selectable Marker
por: Zajdowicz, Sheryl L. W., et al.
Publicado: (2011)

Crystallization and preliminary X-ray study of a thermostable alanine racemase from Thermoanaerobacter tengcongensis MB4. Corrigendum
por: Dong, Hui, et al.
Publicado: (2013)

Role of Alanine Racemase Mutations in Mycobacterium tuberculosis d-Cycloserine Resistance
por: Nakatani, Yoshio, et al.
Publicado: (2017)

Correction to: Inhibitors of alanine racemase enzyme: a review
Publicado: (2018)

d-Cycloserine destruction by alanine racemase and the limit of irreversible inhibition
por: de Chiara, Cesira, et al.
Publicado: (2020)

Selection and characterization of alanine racemase inhibitors against Aeromonas hydrophila
por: Wang, Yaping, et al.
Publicado: (2017)

Knockout of alanine racemase gene attenuates the pathogenicity of Aeromonas hydrophila
por: Liu, Dong, et al.
Publicado: (2019)

Characteristics of alanine racemase in Lactobacillus sakei ZH‐2 strain
por: Kanauchi, Makoto, et al.
Publicado: (2023)

C-Terminal 1-Aminoethyltetrazole-Containing Oligopeptides as Novel Alanine Racemase Inhibitors
por: Kondacs, Laszlo A., et al.
Publicado: (2020)

Glutamate Racemase Is the Primary Target of β-Chloro-d-Alanine in Mycobacterium tuberculosis
por: Prosser, Gareth A., et al.
Publicado: (2016)

Identification of a new alanine racemase in Salmonella Enteritidis and its contribution to pathogenesis
por: Ray, Shilpa, et al.
Publicado: (2018)

Heterologous expression, purification and biochemical characterization of a glutamate racemase (MurI) from Streptococcus mutans UA159
por: Wang, Xiangzhu, et al.
Publicado: (2019)

Crystal Structure of a Thermostable Alanine Racemase from Thermoanaerobacter tengcongensis MB4 Reveals the Role of Gln360 in Substrate Selection
por: Sun, Xiaoliang, et al.
Publicado: (2015)

Structural and biochemical analyses of alanine racemase from the multidrug-resistant Clostridium difficile strain 630
por: Asojo, Oluwatoyin A., et al.
Publicado: (2014)

Characterization of Lactobacillus salivarius alanine racemase: short-chain carboxylate-activation and the role of A131
por: Kobayashi, Jyumpei, et al.
Publicado: (2015)

Structure of the d-Cycloserine-Resistant Variant D322N of Alanine Racemase from Mycobacterium tuberculosis
por: de Chiara, Cesira, et al.
Publicado: (2023)

Structure analysis of free and bound states of an RNA aptamer against ribosomal protein S8 from Bacillus anthracis
por: Davlieva, Milya, et al.
Publicado: (2014)

A Novel PLP-Dependent Alanine/Serine Racemase From the Hyperthermophilic Archaeon Pyrococcus horikoshii OT-3
por: Kawakami, Ryushi, et al.
Publicado: (2018)

Evolutionary fates within a microbial population highlight an essential role for protein folding during natural selection
por: Peña, Matthew I, et al.
Publicado: (2010)

The Short-chain Fatty Acid Propionic Acid Activates the Rcs Stress Response System Partially through Inhibition of d-Alanine Racemase
por: Harshaw, Nathaniel S., et al.
Publicado: (2023)

Regulation of the Gene for Alanine Racemase Modulates Amino Acid Metabolism with Consequent Alterations in Cell Wall Properties and Adhesive Capability in Brucella spp.
por: Hao, Mingyue, et al.
Publicado: (2023)

Glutamate racemase as a target for drug discovery
por: Fisher, Stewart L.
Publicado: (2008)

Purification, crystallization and preliminary X-ray diffraction analysis of RafE, a sugar-binding lipoprotein from Streptococcus pneumoniae
por: Paterson, Neil G., et al.
Publicado: (2006)

Crystal Structures of Lysine-Preferred Racemases, the Non-Antibiotic Selectable Markers for Transgenic Plants
por: Wu, Hsin-Mao, et al.
Publicado: (2012)

Immobilization of an amino acid racemase for application in crystallization‐based chiral resolutions of asparagine monohydrate
por: Carneiro, Thiane, et al.
Publicado: (2020)

A food-grade expression system for d-psicose 3-epimerase production in Bacillus subtilis using an alanine racemase-encoding selection marker
por: Chen, Jingqi, et al.
Publicado: (2017)

The Energy Landscape of Human Serine Racemase
por: Raboni, Samanta, et al.
Publicado: (2019)

Immunogenicity of Recombinant-Deficient Lactobacillus casei with Complementary Plasmid Expressing Alanine Racemase Gene and Core Neutralizing Epitope Antigen against Porcine Epidemic Diarrhea Virus
por: Li, Fengsai, et al.
Publicado: (2021)

Purification, Preliminary Structure and Antitumor Activity of Exopolysaccharide Produced by Streptococcus thermophilus CH9
por: Sun, Naxin, et al.
Publicado: (2018)

Crystallization and preliminary X-ray analysis of an alanine dehydrogenase from Bacillus megaterium WSH-002. Corrigendum
por: Lu, Xiaoyun, et al.
Publicado: (2013)

Localization of Serine Racemase and Its Role in the Skin
por: Inoue, Ran, et al.
Publicado: (2014)

Sociality deficits in serine racemase knockout mice
por: Matveeva, Tatyana M., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_1simnchm7qlfs8rd6agb63etsp