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Nitric oxide controls nuclear export of APE1/Ref-1 through S-nitrosation of Cysteines 93 and 310

Apurinic/apyrimidinic endonuclease 1/redox effector factor-1 (APE1/Ref-1, abbreviated as APE1) is a molecule with dual functions in DNA repair and redox regulation of transcription factors. Accumulated work has shown that the biological activities of APE1 are sensitive to oxidative stress; however,...

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Detalles Bibliográficos
Autores principales: Qu, Jing, Liu, Guang-Hui, Huang, Bo, Chen, Chang
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885639/
https://www.ncbi.nlm.nih.gov/pubmed/17403694
http://dx.doi.org/10.1093/nar/gkl1163