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Quadruplex ligands may act as molecular chaperones for tetramolecular quadruplex formation
G-quadruplexes are a family of four-stranded DNA structures, stabilized by G-quartets, that form in the presence of monovalent cations. Efforts are currently being made to identify ligands that selectively bind to G-quadruplex motifs as these compounds may interfere with the telomere structure, telo...
Autores principales: | Cian, Anne De, Mergny, Jean-Louis |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885647/ https://www.ncbi.nlm.nih.gov/pubmed/17395639 http://dx.doi.org/10.1093/nar/gkm098 |
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