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Topoisomerase II, scaffold component, promotes chromatin compaction in vitro in a linker-histone H1-dependent manner

TopoisomeraseII (Topo II) is a major component of chromosomal scaffolds and essential for mitotic chromosome condensation, but the mechanism of this action remains unknown. Here, we used an in vitro chromatin reconstitution system in combination with atomic force and fluorescence microscopic analyse...

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Detalles Bibliográficos
Autores principales:	Hizume, Kohji, Araki, Sumiko, Yoshikawa, Kenichi, Takeyasu, Kunio
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2007
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885653/ https://www.ncbi.nlm.nih.gov/pubmed/17430970 http://dx.doi.org/10.1093/nar/gkm116

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